GLP-1 agonists can be helpful for appetite control if that’s a limiting factor during prep. However, when the foundation (nutrition, training, sleep, and hormone levels) is already optimized, the focus shifts to precise interventions that support fat loss while preserving lean mass.
5-Amino-1MQ tends to yield better results in patients with metabolic syndrome or insulin resistance, rather than in already lean, high-performing individuals.
CJC/Ipamorelin is more appropriate in this context, especially for its synergy with training and ability to preserve muscle. Dosing frequency is critical—ideally 2–3 times daily, timed around training and fasting windows.
Morning and bedtime doses are easy to maintain.
A post-workout third dose (with food 30 minutes after) is optimal but may be challenging due to frequent meals in this population.
BPC-157 can be added to enhance growth hormone receptor density, improving response to CJC/Ipamorelin.
Tesamorelin is a more potent GH-releasing peptide, often used in the bodybuilding population, and may be considered if more aggressive fat loss is required without compromising muscle.
iCell Water (creatine + amino acids) is another valuable addition for this population. It supports workout quality, recovery, and lean mass retention during a caloric deficit.
