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Performance Collagen™

Fortigel hydrolyzed collagen is a novel ingredient aimed at joint cartilage regeneration, backed by clinical evidence for reducing pain, enhancing mobility, and promoting long-term cartilage health safely.
Collagen’s significance extends to skin elasticity and hydration; potentially enhancing skin moisture, elasticity, and reduce wrinkles for a more youthful appearance.

Details

Per Bottle 20 servings
Serving Size 1 scoop
Directions Take one scoop daily.

Supplement Facts

Amount per serving
Protein 15g 
Vitamin C (Ascorbic Acid) 90mg 
Iron 0.37mg 
Sodium 135mg 
FORTIGEL® (Collagen Hydrolysate) 5g
Bovine Collagen Peptides 10g
Sodium Chloride 3g 
† Daily Value (DV) not established

Cellular Pathways

A positive effect of collagen peptides on the regeneration of hyaline cartilage was observed in cultured chondrocytes.

Hyp-Pro-Gly peptides

The stimulation of the extracellular matrix (ECM) synthesis is probably caused by specific Hyp-Pro-Gly containing peptides with a molecular size <10 kD.

Stimulate the growth and activity of fibroblasts, the cells responsible for producing collagen in the skin and other connective tissues.

Why this matters:

As individuals age, collagen levels decrease, leading to less flexible and more brittle cartilage. Aging-related changes increase collagen cross-linking, stiffening cartilage and making it prone to fatigue failure. Structural collagen changes, including degradation, are associated with skin wrinkling, bone deterioration, and cardiovascular and respiratory issues. Cartilage degeneration, a result of aging, can lead to arthritis, also known as degenerative joint disease.

Clinical Studies

Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides.

  • 5g supplementation of FORTIGEL treatment was shown to decrease knee pain and stiffness and increase physical function after 6 weeks

  • After 12 weeks 40% of patients reported no knee pain and 70% achieved a positive effect of therapy

Clinical Studies

Synergy with Pentosan Polysulfate, BPC-157, GHK-Cu

Hydrolyzed Collagen is a key component in proteoglycans and collagen type II formation which can help repair cartilage degradation and decrease joint pain, typically used in joint and inflammatory pain protocols.

References:

  1. Zdzieblik D, Oesser S, Gollhofer A, König D. Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides. Appl Physiol Nutr Metab. 2017 Jun;42(6):588-595. doi: 10.1139/apnm-2016-0390. Epub 2017 Jan 24. Erratum in: Appl Physiol Nutr Metab. 2017 Nov;42(11):1237. PMID: 28177710.
Performance Collagen™